Niacin in the prescription form "Niaspan"! It worked for me.

In October 2007 my LDL and Lp(a) cholesterol levels were high along with low levels of HDL. I was told to take 40mg of Simvistatin. After the last blocked artery in March 08 my physician added 500mg daily of prescription Niaspan. I increased the dosage by 500mg every two weeks til I reached a therapeutic dosage which I am now on of 3,000mg daily. Obviously, they keep monitoring my Liver Enzyme levels for any toxicity issues. My liver enzymes to date have actually gone down. I was told by my gastroenterologist that years of high cholesterol along with high glycemic diet had actually caused me to have a non-drinking fatty liver. The cholesterol medicine has allowed my level to process the fat or I assume the cholesterol thus reducing enzyme levels.

The Niaspan (prescription Niacin) alone has helped to change my lipid profiles particularly the Lp(a) reduction and increase of HDL. The Niaspan has decreased the LDL's from a high of 175 to 76. Also, Niaspan is the only prescription that I was told reduces the Lp(a). It has dropped from 85 to 19. The Niaspan has also increased my HDL from 34 to 52. Now keep in mind that I am also on 40mg of Simvistatin but the Lp(a) and the HDL levels were not changed while on the Simvistatin alone. I have also seen a change in the LDL particle size from small to large. This is particularly important because if two people had the same LDL levels of 175 one may not be at risk as much as the other because one may have large particle LDL while the other has small particle LDL. Mine obviously was the small particle LDL. But it seems the Niaspan is changing the profile of the LDL also!

Taking the Niaspan by itself would be a closer natural alternative to regulate cholesterol than the statins although to reach a decision of taking this drug alone would obviously be determined with proper submolecular cholesterol testing in conjunction with consultation with your physician. The Niaspan though in my case has delivered beneficial results which include decreasing LDL and Lp(a) levels along with raising HDL numbers. I don't believe there is any other prescription which does all three simultaneously! http://www.niaspan.com/